Antibodies and Antigens
CEA
Epitope characterization has revealed five major antigenic domains of CEA, “Gold epitope 1-5”. High affinity IgG1 monoclonal antibodies (4x10-11 mol/L) against “Gold epitope 5”, 12-140-1 MAb and “Gold epitope 4”, 12-140-10 MAb, are offered for serological and immunohistochemical determination of CEA. For the development of sensitive and specific assays for determination of CEA, the 12-140-10 MAb is recommended as catching antibody in combination with labeled 12-140-1-MAb as detecting antibody.
| MAb | Isotype | Form | Prod. no. | Comments |
|---|---|---|---|---|
| 12-140-1 | IgG1 | Purified | 401-01 | Gold epitope group 5 |
| 12-140-10 | IgG1 | Purified | 402-01 | Gold epitope group 4 |